Mayo Clinic Announces Collaboration on Genotyping Test for Warfarin Sensitivity

ROCHESTER, Minn. — Mayo Clinic today announced that it has reached an agreement with Rheonix, Inc. to collaborate on the performance of a genotyping test for warfarin sensitivity in clinical and research settings. The genotyping test will be available for all patients of Mayo Clinic and is the subject of ongoing research for improved anticoagulation therapy. Additionally, the test will be offered through Mayo Clinic’s reference laboratory, Mayo Medical Laboratories, to clients throughout the world.

“The common anticoagulant warfarin (Coumadin) is prescribed to prevent and treat the formation of blood clots,” says Dennis O’Kane, Ph.D., associate professor in the Department of Laboratory Medicine and Pathology. “Until now, determining the correct dosage to prescribe a patient has been a matter of trial and error. Using this genetic test better enables physicians to administer suitable doses of warfarin individualized to each patient and to identify if they are at risk for forming blood clots due to subtherapeutic dosing, or at risk of severe bleeding due to overdosing of warfarin. This new test builds upon Mayo Medical Laboratories’ continuing efforts to develop useful, cost-effective tests to assist in providing the best management of warfarin for patients."

“This collaboration is an important step in bringing commercial reality to the longpromised potential of pharmacogenomic testing for well-established pharmaceuticals and for next-generation pharmaceutical development,” says Tony Eisenhut, president of Rheonix, Inc. “Through this collaboration, we hope to assist the medical community in providing the best patient care possible.”