Below are relevant publications for applications of Rheonix technology in the Research and Clinical realms. For publications pertaining to Food and Beverage testing, please click here.

Utilizing the Rheonix NGS OnePrep™ Solution to automate the Takara Bio ThruPLEX® Tag-Seq HV library preparation kit

B.J. Kim1, H. Zhu1, R. Yasmin1, L. Sherlin2, J. Laliberte3, P. Martin2, A. Farmer2, H. Higgins1 B. Schwartz1 and R. Montagna1
1Rheonix, Inc., Ithaca, NY, 2Takara Bio USA, Inc., Mountain View, CA, 3Takara Bio USA, Inc., Ann Arbor, MI

Whole-Genome Sequencing Analysis of Clinically Significant Carbapenem-Resistant Enterobacteriaceae Using the Rheonix NGS OnePrep™ Solution Automation Platform

Deisy Contreras1, Hui Zhu2, Beum Jun Kim2, Rubina Yasmin2, Richard Montagna2 and Shangxin Yang1
1Department of Pathology and Laboratory Medicine, University of California Los Angeles, CA 90049, 2Rheonix, Incorporated, Ithaca, NY 14850

Fully Integrated Automation of NGS Library Preparation for Foodborne Pathogens

H. Zhu1, B Kim1, R. Yasmin1, G. Kastanis2, M. Allard2, and R. Montagna1
1Rheonix, Inc., Ithaca, NY, 2Center for Food Safety & Applied Nutrition/FDA, College Park, MD
Association of Molecular Pathology Annual Meeting (2018)

Fully automated and integrated multiplex detection of high consequence livestock viral genomes on a microfluidic platform

Oliver Lung, Mathew Fisher, Anthony Erickson, Charles Nfon, Aruna Ambagala
Canadian Food Inspection Agency
Transboundary and Emerging Diseases (2018)

Fully Automated DNA Isolation and NGS Library Preparation

H. Zhu1, B.J. Kim1, R. Yasmin1, S. Valiyaparambil2, B. Marzullo2, M.J. Buck2 and R. Montagna1
1Rheonix, Inc., Ithaca, NY, 2State University of NY at Buffalo, Buffalo, NY

American Association for Clinical Chemistry Annual Meeting (2018)

Fully Automated Molecular Diagnostics

Rheonix, Inc.

Fully Automated DNA Isolation & NGS Library Preparation

H.Zhu1, BJ Kim1, R. Yasmin1, S. Valiyaparambil2, MJ Buck2, and RA Montagna1
1Rheonix, Inc., Ithaca, NY, 2State University of NY at Buffalo, Buffalo, NY

American Society for Microbiology Annual Meeting (2017)

A Modifiable Microarray-based Universal Sensor: Providing Sample-to-results Automation

Rubina Yasmina, Hui Zhua, Zongyuan Chena,b, Richard A. Montagnaa,*
aRheonix Inc., 10 Brown Road, Ithaca, NY 14850, USA
bThermo Fisher Scientific, South San Francisco, CA, USA
*Corresponding author

Heliyon (2016)

A Rapid, Self-confirming Assay for HIV: Simultaneous Detection of Anti-HIV Antibodies and Viral RNA

Zongyuan Chen1, Hui Zhu1, Daniel Malamud2,3, Cheryl Barber2, Yhombi Yvon Serge Ongagna2, Rubina Yasmin1, Sayli Modak2, Malvin N. Janal2, William R. Abrams2 and Richard A. Montagna1*
1Rheonix, Inc., Ithaca, New York, USA
2New York University College of Dentistry, Department of Basic Sciences, New York, USA
3New York University School of Medicine, Department of Medicine, New York, USA

Journal of AIDS & Clinical Research (2016)

Determination of Genotypes Using a Fully Automated Molecular Detection System

Gwendolyn Spizz, PhD; Zongyuan Chen, PhD; Peng Li, PhD; I. Cristina McGuire, PhD; Paulina Klimkiewicz, BS;
Devin Zysling, PhD; Rubina Yasmin, PhD; Whitney Hungerford, BS; Benjamin Thomas, BS; Gregory Wilding, PhD;
Gregory Mouchka, MS; Lincoln Young, BS; Peng Zhou, PhD; Richard A. Montagna, PhD
Rheonix, Inc., USA

Archives of Pathology & Laboratory Medicine (2015)

Automated Sample-to-Results Analysis of Clinical Specimens for Sexually-Transmitted Infections

Gwendolyn Spizz, I. Cristina McGuire, Kevin Kowitski, Whitney Hungerford, Rubina Yasmin and Richard A. Montagna, Rheonix, Inc., USA

American Association for Clinical Chemistry Annual Meeting (2014)

Microfluidics for IVD: In Pursuit of the Holy Grail

Dr. Peng Li, Rheonix, Inc, USA

Microfludics (2012)

Development of a Generic Microfluidic Device for Simultaneous Detection of Antibodies and Nucleic Acids in Oral Fluids

BioMed Research International (2013)

Rheonix CARD® Technology: An Innovative and Fully Automated Molecular Diagnostic Device

Point of Care:  The Journal of Near-Patient Testing & Technology (2012)

Evaluation of a Microfluidic System for Performance of Fully Automated Companion Diagnostics for Personalized Medicine

AACC Oak Ridge Conference (2012)

MLO Clinical Issues – Meeting the Technical Challenges of Personalized Medicine and Companion Diagnostics

Medical Lab Observer (2012)

Two-step DNA Isolation Followed by PCR in a Fully Automated System to Detect Septicemia Agents in Whole Blood

American Association for Clinical Chemistry Annual Meeting (2011)

Rheonix CARD® Technology: A Fully Automated Molecular Diagnostic for Infectious Diseases

Association for Molecular Pathology Annual Meeting (2010)

Automatic and Rapid Molecular Detection of E. coli and Enterococci in Raw Recreational Water Samples Using the Fully Automated Rheonix CARD® Technology Platform

Great Lakes Beach Conference meeting (October 2010)

Fully Integrated, Automatic, and Rapid Molecular Detection and Identification of 20 Clinically Relevant HPV types Using the Rheonix CARD® Platform

American Association for Clinical Chemistry Annual Meeting (2010)

Rheonix CARD® Technology for Rapid and Automatic Determination of SNP Profile for Pharmacogenomics

American Association for Clinical Chemistry Annual Meeting (2010)

Rapid Molecular Detection of Sexually Transmitted Infections Using a Fully Automated, Microfluidic Rheonix CARD®

American Association for Clinical Chemistry Annual Meeting (2010)

Weak solvent based chip lamination and characterization of on-chip valve and pump

Biomedical Microdevices (2010) 12:821-832, Published online, 5 June 2010